This is achieved through whole genome sequencing, analyzing all genes at once to understand the overall genetic characteristics and determine the most suitable medical approach accordingly. It helps grasp an individual’s unique health traits and direction, identify diseases they are prone to, and design a personalized health plan. By adjusting acquired risk factors, diseases can be prevented or early pathological changes can be detected. The so-called constitution or susceptibility to diseases is determined by genes. Nowadays, whole genome sequencing can comprehensively examine all genes to understand one’s potential constitution. Combined with the analysis of acquired lifestyle risk factors, individuals can adjust their habits that require special attention, reducing the chance of disease occurrence. This makes disease prevention more precise, concrete, and personalized. This advanced medical technology is called “Whole Genome Precision Preventive Medicine.” The goal of this medical approach is to assist in the early detection and prevention of common modern diseases, including cancer, dementia, metabolic disorders, and cardiovascular diseases. The main causes of these diseases are inevitably related to genetics to some extent. Genes determine metabolism, immunity, and the repair function of abnormal cells. Together with environmental factors and acquired lifestyle habits, they interact to cause these modern diseases. The innate personal genetic information is recorded in the genome. Each individual has different diseases they are prone to, which may be caused by a single gene mutation or by the combined effect of multiple genes with smaller individual impacts. Currently, through medical center-level whole genome sequencing, both single-gene and polygenic analyses are conducted simultaneously, making disease prevention more precise and effective.